I'm guessing you've not read them?
The gimmick of the series is that all sentient species were uplifted from non-sentient animals, and they were uplifted by species that were uplifted, which in turn were uplifted... and none of them knows by whom or by what. The "progenitors", the hypothesized first sentients that uplifted a presumed first generation, are lost to prehistory and nobody knows.
So there is a shared culture and a small degree of shared biology, because each generation of uplifters uses existing models of sentient species to model new sentient species. There are only so many ways to invent the wheel, although Brin was very imaginative indeed in this.
Humans were not uplifted; we're called "wolflings" and as a terrifying novel abomination would have been exterminated upon discovery, were it not for the novels' future setting having us already started work uplifting dolphins, chimpanzees, orang utans and a handful of other species. If humans were not a progenitor species the aliens would have extirpated us -- but we have client species of our own.
He does have answers to most of the objections one might come up with.
Brin's ideas were influenced by Larry Niven, and riffed upon by Terry Pratchett in his early SF works. Later Brin novels riff on ideas from his own earlier ones.
In their time, in the 1980s, I really enjoyed them. I own them all, several in hardback. I haven't re-read them in decades so I don't know how they hold up, but Brin is alive and still active.
Anyway, point is that for the kinds of races likely to get their manipulators on a fresh planet, direct colonization is often way down their list of priorities. (And perhaps most of their population is already in a Dyson swarm or something.)
Also, the deep history of visits means there's been time for a lot of similar biology to spread around.
There are also significant numbers of extremely agressive and militaristic civilisations, mostly held back by the laws and customs of setting, who would gleefully seek out and destroy anyone not following along.