I regularly have users run Sysprof and upload it to issues. It's immensely powerful to be able to see what is going on systems which are having issues. I'd argue it's one of the major reasons GNOME performance has gotten so much better in the recent-past.

You can't do that when step one is reinstall another distro and reproduce your problem.

Additionally, the overhead for performance related things that could fall into the 1% range (hint, it's not much) rarely are using the system libraries in such a way anyway that would cause this. They can compile that app with frame-pointers disabled. And for stuff where they do use system libraries (qsort, bsearch, strlen, etc) the frame pointer is negligible to the work being performed. You're margin of error is way larger than the theoretical overhead.