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Comment by throwawaymaths | Hacker News Reader

The issue with ADCs is you're putting a really giant homing system on a tiny warhead. How many molecules of X does it take to kill a cell? There is one really good warhead candidate, but un?fortunately it's illegal to research

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What candidate are you referring to?

Nope. Don't want to be on surveillance lists, even with an anon account. Was researched in the 80s, before we knew enough about the antibody side to make a good go of it. then dropped for obvious reasons (it didn't work which makes sense in retrospect given the crude conjugation strategy plus the restrictedness of the warhead side). That's all I'll say.

Probably enough info for you to figure it out if you're smart. Don't wind up in jail.

Are you referring to monoclonal antibodies? For which a Nobel Prize was awarded in 2018, and research has continued since the 80s?

No, that's the "homing system" side of this analogy. GP is talking about some sort of poison (chemo), but I don't know which one or what the paranoia is about.

Yeah there's stuff that will get you on lists especially since 9/11. But some of them have been restricted since before that, though de facto unenforceable. Today there is the ability to ingest huge volumes of data. I just don't want to deal with the pain in the ass even if I'm found innocent.

Your paranoia is not justified. merely mentioned potential treatments (even ethically questionable ones) does not get you on any "watchlists".

Just say what it is you're referring to, or don't mention it at all.

I will do this for you. List 20 compounds surveiled by the US government for potential association with terrorist groups in a comment under your account below this comment and I will answer yes/no if it is in the group as a whole.

Merely mentioning illegal/regulated drugs does not get you on a watch list. Answering yes/no to a list does not protect you. I will not continue to engage.

That's fine if you don't respect my boundaries I don't need your engagement

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