I word say: it depends. I must've wasted days of my life trying to reverse engineer android apps with pinned certificates. It's crazy how hard it has become to just inspect the traffic on my own device that I bought and own.
[0] - https://httptoolkit.com/
No manual setup or config, just click a button and done.
Avoiding in-depth detection is left as an exercise for the reader, although there are a small set of existing countermeasures in there. In practice, there is definitely a very long tail of further cases of increasing complexity, with diminishing returns on automated solutions, but it turns out in practice you can automate quite a long way down that path and cover most normal cases.
Flutter is the one awkward case here I've found that doesn't fully work. Very interested to see if there are generalizable automated solutions there, or if the recent fork announcements mean the slow death of flutter anyway...