I think that the compilation and optimization step, as a black box, is a disservice for highly reliable software development. Compiler and optimizer bugs are definitely a thing. I was bitten by one that injected timing attacks into certain integer operations by branching on the integer data in order to optimize 32-bit multiplications on 8-bit microcontrollers. Yeah, this makes perfect sense when trying to optimize fixed point multiplication, but it completely destroys the security of DLP or ecDLP based cryptography by introducing timing attacks that can recover the private key. Thankfully, I was fastidious about examining the optimized machine code output of this compiler, and was able to substitute hand coded assembler in its place.