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Comment by Narkov | Hacker News Reader

> Ozempic has entered the chat.

This honestly feels like the kind of thing where 20 years from now we'll be more aware of the side effects and people will shake heads about how stupid "we" were today.

If this is going to be an exception, it'd be truly interesting.

There are already a bunch of studies showing that the ozempic causes massive muscle loss and lessens bone density. And before anyone remarks "just do resistance training", I doubt the people that take the easy solution will do it in conjunction.

Do they cause it in excess of normal weight loss in the same time period? I'm asking because regular weight loss that's quick will have both of these effects too.

> Do they cause it in excess of normal weight loss in the same time period?

I think you mean diet and exercise when you say 'normal'. Its not possible to have that much 'normal weight loss' in the 'same period'.

Correct me if I'm wrong but Ozempic doesn't cause you to lose weight, instead it controls your appetite. It's not something like DNP, right?

'Normal weight loss' here refers to eating the same amount of calories without taking Ozempic. You should lose weight at the same speed as with Ozempic, because it's the calories that matter when it comes to fat loss.

Weight loss always comes with some muscle loss and bone density loss, because the structure now supports less weight than before, and our bodies dislike to maintain muscle apparatus beyond what is necessary.

Unless Ozempic causes significantly more muscle loss than other ways of losing weight, that news isn't really news.

Conversely, this is also why the strongest powerlifters are huge heavy guys. They aren't necessarily healthy. But they are strong.

Ozempic doesn't cause that, losing weight via diet does. Weight Watchers moms get the same thing.

The only people who don't are people who lose weight through resistance training. Which is a small minority - because we have a HUGE diet culture!

Its a transfer of wealth from the fast food conglomerates to Novo Nordisk. They won't take this lying down. Ozempic resistant foods are coming.

I cannot possibly even imagine how this could be the case, considering just how deadly and miserable obesity is. I don't see how we can hypothetically "solve" obesity and then go back to an obese population because the drug makes you nauseous or something. And that's not even considering the, what I can only assume to be, trillions of dollars of healthcare cost savings over time.

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