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Comment by awestroke | Hacker News Reader

I wonder how much of an uphill battle it will be to get psilocybin approved for therapeutic use compared to synthetic psilocybin analogues that are being trialed right now. Psilocybin can't be patented and it's already scheduled as a narcotic everywhere.

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The 2018 Hemp Farm bill gave the balls back to the citizens that the 2013 Analag act neutered.

Seeing mushroom extracts with all the alkaloids included besides psilocybin at gas stations may be a temporary point of stability until I can go to the "21+" store in 2030 to get my preferred arylcyclohexylamine and phenylethylamine variant.

From what I understand, those “magic mushroom” edibles sold in head shops and gas stations are amanita muscaria derived, which is a completely different psychoactive substance with different alkaloids. Toxic to the liver too, in ways that a cubensis is not.

Northern shamans drank reindeer urine after the animals had eaten amanita muscaria. Passing through the animals reduced the toxic component but left enough alkaloid to trip balls. Maybe the gas station edibles have removed the toxin.

signs point to no:

https://www.cbsnews.com/news/magic-mushrooms-found-in-recall...

Personally, I trust gas station drugs as much as I trust their tuna sandwiches

I was aware but I should know to put disclaimers in drug posts on HN at this point, as others may not be; thank you.

That being said, it did have an uncomfortable but brief 'burning/cleansing' feeling reminiscent of Lyseragmides that that most tryptamines / 4-aco-DMT / penis envy / cubensis / 5-MEO-[xxx] did not, and more visual distortions with notably less headfuckery / low body load.

I recommend a single try; the tolerance seemed to eliminate effects nearly immediately.

Geneva is home to the only Swiss hospital offering psychedelic-assisted therapy. [0]

Also, Peter Gasser, a Swiss therapist acquainted with LSD during the 1988-1993 window, was granted approval to carry out the first controlled study of LSD-assisted psychotherapy in more than 40 years. [1]

[0] https://www.swissinfo.ch/eng/science/can-psychedelics-therap...

[1] https://theswisstimes.ch/lsd-and-magic-mushrooms-how-switzer...

I'm taking a prescription med that is basically a schedule 1 drug that's been very slightly modified and declared schedule 3 and prescribed through a tightly controlled program. I'm even taking a generic version.

Purely out of curiosity, which drug is this, if you don't mind me asking?

Sodium oxybate. Active ingredient is GHB. I was stunned to find out this was a therapeutic but apparently it was developed for potential therapies and was only coincidentally discovered to be intoxicating. I used to suffer debilitating cataplexy and sodium oxybate has nearly wiped it out.

Right, GHB is an interesting one. It's always fascinated me how most recreational drugs are a wonderdrug for at least one medical condition. There are a couple of exceptions of course. Like synthetic cannabinoids. But even ethanol can be used as an antidote for methanol poisoning.

For me it's amphetamine. I have severe dehabilitating ADHD-C and lisdexamphetamine has completely changed my life.

It's already being used in therapy. Oregon is giving licenses.

https://www.oregon.gov/oha/ph/preventionwellness/pages/psilo...

In Oregon enforcement of what passes for our drug laws here is so lax (cops quiet quit long before covid) that it's de-facto legalized.

I've literally walked down Portland and had random homeless people unprompted yell out "Want to buy some shrooms?"

There have been unlicensed openly practicing shrooms businesses which survived far longer than one would expect for such a "regulated" industry.

I doubt about everywhere, as shrooms are sold in shop around here.

Where is here?

california has mushroom stores

Clearly not North America

In the US, those aren’t from mushrooms that contain psilocybin or related neurotransmitter analogs

It definitely happens:

https://www.seattletimes.com/business/oregon-store-allegedly...

https://www.sfgate.com/cannabis/article/sf-magic-mushroom-ch...

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