The main thing I missed was the ability to block arbitrary elements with the zapper. I use this for more than just ads, so losing it is a real loss in functionality. Otherwise it worked fine.
Never leaving your subscriptions (never using the algorithm recommended feed) is not a solution because of second-hand toxicity, e.g. political posts in meme subreddits in an election year.
If anyone knows of a solution that works in Manifest V3 I'd love to hear it!
AdGuard AdBlocker (MV3 Beta): https://chromewebstore.google.com/detail/adguard-adblocker-m...
Copy and pasting the ublock custom filters into AdGuard seems to work.