I got it running locally like this, using uv to manage dependencies:

    git clone https://github.com/redimp/otterwiki.git
    cd otterwiki

    mkdir -p app-data/repository
    git init app-data/repository

    echo "REPOSITORY='${PWD}/app-data/repository'" >> settings.cfg
    echo "SQLALCHEMY_DATABASE_URI='sqlite:///${PWD}/app-data/db.sqlite'" >> settings.cfg
    echo "SECRET_KEY='$(echo $RANDOM | md5sum | head -c 16)'" >> settings.cfg

    export OTTERWIKI_SETTINGS=$PWD/settings.cfg
    uv run --with gunicorn gunicorn --bind 127.0.0.1:8080 otterwiki.server:app

I filed an issue here suggesting that for the docs https://github.com/redimp/otterwiki/issues/146 - and also that it would be great if getting started could be as simple as this:

    pip install otterwiki
    otterwiki \
      --repository app-data/repository \
      --sqlite app-data/db.sqlite \
      --secret-key secret1 \
      --port 8080