For now your best bet is probably to use a Firefox fork (Icecat will probably not shit the bed, but there's many other forks although a good chunk of them also modify the source code in ways that might not be desirable to casual browser users since they started usually with the goal to privacy harden Firefox and privacy focused forks have a bad habit of disabling features you probably do want enabled) or a user.js for Firefox to turn off undesirable features, at least until the situation becomes truly unusable; not sure what the best choice is after that because none of the Firefox forks have the manpower to step up and become a new main browser.
I remember up until around 10 to 15 years ago when Mozilla enjoyed seemingly limitless good will from basically anyone who had anything to do with computers.
Now they're arguably more reviled than even Big Tech, and rightfully so especially since they're deceiving about it.
They have some good stuff like offline page translation.
But most importantly they have a good review process for popular browser extensions. Google controls Chrome store, and they have conflict of interest when it comes to hosting stuff like Ublock.
So for daily browsing locked down Firefox. For banking and office stuff vanilla Chrome.
It's serendipitous you mentioned that extension, because Mozilla recently came under fire after its treatment of that developer[1], and people started talking about how tedious it is to publish extensions. Mozilla is now also an ad company, so it has the same conflict of interest as Google.
Ublick Origin is different from "Ublock Origin Lite"
So, a big question then is if Google, Apple, or Mozilla decide to change their engine in such a way that it would improve user tracking on the web how many of these custom browser companies and individuals (Vivaldi, Brave, Arc, Tor, folks, etc.) would be willing to undo those changes, or add code to mitigate the tracking? And then how many of them will keep migrating their patches from one version of the engine to the next? And how many of them will continue doing so when the engine maintainers will actively try to make this work harder? And how many investors will keep giving money to these browser companies?
The web is very vulnerable, and Mozilla with its board slowly leeching off all the resources out of it has long been loosing its ground for a long time. I'm afraid that we are at a point when the only way to preserve user privacy is via regulatory means. EU is clumsy, but at least they make the user tracking more annoying for advertisers, and some actors like Apple would be more hesitant to blatantly add ad supporting code to WebKit just to avoid further confrontations with the EU.
There are some Firefox forks that are OK, like librewolf and icecat.
Sadly then this becomes hard to maintain for non-IT people (i.e. the majority).