I'm guessing most people, like me, first heard about both Clojure and Datomic from one of Hickey's famous talks about software development. Coming from one of those, I guess it's a bit easier to understand what the various concepts and words mean from Datomic's website for example.
I guess the easiest way to put it: Datomic is a append-only (deletions via "retraction" records) database that lets you query through time (also called "Bitemporal modeling" with fancier words).
The features/benefits page I think is pretty clear (https://www.datomic.com/benefits.html) but again, might just be my familiarity speaking.