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When I took omega-3 in addition to duloxetine, I got terrible brain zaps the whole day.

That's interesting, zaps are a withdrawal syndrome of SSRIs (and duloxetine).

Yep. That's where I knew brain zaps from, because I previously experienced them when coming off SSRIs.

I had them after an accidental too big MDMA dose, after which I felt depressed for a few weeks.

Buspirone (an anti-anxiety) gave me brain zaps within an hour of taking it. Didn't seem to help with the anxiety at all though...