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Are these filters sufficient to filter out microplastics?

Yes. And particles down to 0.3 microns.

My understanding is that the health benefits are most pronounced from avoiding smoke and fine dust particles which don't necessarily have a lot to do with plastic, but it's a good recommendation regardless.

There is significant evidence linking PM2.5 concentrations and health (which is a common metric about fine particles in the air of a particular size, in this case 2.5 micron range)

To add to this, hepa filters are extremely effective. They are rated at something like 99.95%. That is the rating for the size of particle that they are worst at filtering. Particles both smaller and larger are filtered at a higher rate. This is also only for air passing through the filter once, if you have a air purifier running in a small room it will pass all the air through it multiple times, completely cleaning the air of basically anything that is not gas or vapour. Of course new particles can come into the air from various sources. It’s kinda magical that we can have this technology that is affordable and actually genuinely does what is advertised

They are so effective that they will literally filter a bad smell out of a room assuming it’s not a gas that’s making then smell.

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