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I find Quod Libet to be my tool of choice, now. The query language is a bit ridiculous, but Mutagen is great for cleaning up crappy tags from my mp3 purchases. Despite being a PyGTK app, it has been fairly responsive and snappy despite my ridiculous media-hoarding habits.

http://code.google.com/p/quodlibet/

Same. Winamp is the only player I use. The feature that sets it apart: I set a playlist, and _the playlist stays around_ until I change it, no need to explicitly save anything and it survives restarts. WMP and iTunes always forget what you were playing across sessions, at least the last time I tried them.

I use MPD. It's really lightweight, have a simple and straightforward concept of playlists and I can use the standard *nix tools to mutate and create playlists.

http://mpd.wikia.com