This is a perfect reason to install uBlock Origin.
For anyone who isn’t running Chrome, that is.
https://adguard-dns.io/en/blog/encrypted-dns-ios-14.html
So yeah. While it won’t kill ads in apps like YouTube or Pinterest, it will kill nearly all ads in web pages and apps that source their ads from external providers.
I'd have little problem with static ads in webpages that looked like the ones in magazines I grew up with.
To be clear, I also use an adblocker and I don't have any good answers.