C.S. Peirce, who is known for characterizing abductive reasoning and had a considerable on John Sowa’s old school AI work, had an interesting take on this. I can’t fully do it justice, but essentially he held that both matter and mind are real, but aren’t dual. Rather, there is a smooth and continuous transition between the two.
However, whatever the nature of mind and matter really is, we have convincing evidence of human beings creating meaning in symbols by a process Peirce called semiosis. We lack a properly formally described semiotic, although much interesting mathematical applied philosophy has been done in the space (and frankly a ton of bullshit in the academy calls itself semiotic too). Until we can do that, we will probably have great difficulty producing an automaton that can perform semiosis. So, for now, there certainly remains a qualitative difference between the capabilities of humans and LLMs.