For me I'll never go back to normal front-end work after doing Blazor with C#. It's the nice bits of React (reusable code) but the flexibility of never having to decide between front-end only focused code, or some back-end powered AJAX style code, that is transparently rendered for you. You never have to touch JavaScript, but there's ways to do so.

WASM is the best thing that ever happened to the web. When other major web frameworks adopt template engines that compile to WASM, we will see a shift in focus on JS heavy frameworks, and just people building things instead of fighting and trying to remember all the weird quirks of JavaScript.