It seems unlikely that airlines are going to lead the way here, just due to economics I think it's going to be the bizjet market leading the way(1).
So the obvious choice for domestic flights would be Russia: rich oligarchs, huge country, loose enforcement of laws. Unfortunately for the world that is impossible for the foreseeable future.
The next best target is going to be transpac- IFF they can get sufficient range. So wealthy businessmen who have to do a lot of travel between Asia and North America is a reasonable market, so long as they can do supersonic the entire way. If you have to stop and refuel I suspect that the numbers don't work so well. If they can only do a translant without refueling the market is going to be people who want the prestige of having the coolest toys, and Boom is stuck trying to compete with Gulfstream G650 on prestige.
1: R.E.G. Davies explained it best, the problem with commercial supersonic is that the earth is rotating. For commercial airlines, the killer app for selling "expensive but gets you there faster" flights is the ability to get someone to a meeting the same day versus having to travel the day before. If you can save an executive a day that is hugely valuable and worth the company paying a premium for. If you can't, paying extra for a faster flight just isn't worth that much.
As a thought experiment, let's say that everything else is exactly the same, but at the end of the runway a Star Trek transporter beams the plane directly to the runway at the destination. So the executive wakes up in NYC at 5:30AM, is out of the house by 6AM, takes an hour to get to the airport, that's 7AM. It's an international flight so they need to go through extra checks, it's 8AM when their flight leaves for Paris. It is beamed directly to CDG, thanks to time zones it's now 2PM. Then it takes another hour to get through passport control etc. and it's 3PM, and another hour for ground travel in Paris and even without the flight taking any time at all it's already 4PM after waking up at 5:30AM. That's tough to make meetings work. (Obviously the return trip can achieve this meeting on day 1 effect, but a commercial airline you can only charge good prices for on half of its legs is going to be tricky to earn its money back.)