Decades ago I learned dvorak and used it exclusively for about a year. I honestly felt no benefits. If anything it made things more of a pain in the ass because many common commands (e.g. Ctrl-C Ctrl-V) are where they are because of their locations on a qwerty keyboard. You can re-map shortcuts but I still find myself using devices that aren't my own often enough that I find it annoying.
I remember one funny instance where I had to remote desktop into a shared server, and I remapped to dvorak and forgot to change it back, and then when someone else remoted in they thought their keyboard was possessed.