Maybe it’s just me, but I find that I will frequently mistype switching between different warty keyboards (eg, standalone mechanical vs laptop)
I can mentally switch over to dvorak and program for a while, mentally swap back, and type normally for other things. I mainly switched the default layout back to qwerty because I was tired of remapping all the keys in every game I play. Sometimes when I come into work on a Monday morning I'll type gibberish for a couple of sentences then mentally flip back to qwerty and be fine.
I get your point in principle. I actually switched to Colemak in college, and it worked really well. Then I got a job doing IT support and it was a pain in the butt to keep switching every time I interacted with a customer laptop.
But now I remote work from home. I can’t remember the last time I touched a keyboard that wasn’t mine.
I've never felt any discomfort from qwerty, so, no, this business about increased ergonomics and comfort is a false promise to me.
I have, however, helped multiple people who thought they had problems in their hands and wrists who actually had problems in their necks and shoulders, and showing them diagrams of the brachial plexus nerves helped them eliminate their pain through posture changes.