I must say, I still work a hybrid schedule, much from home (I live in the neighborhood too). I also must day that opening a physical location in SF has been one of the best investments I have ever made in my business.
I now have people, target customers I used yo have to work hard to find and get time with, introducing themselves to ne coming by to day hello daily. Same thing with startups and VCs, there are a dozen or more VCs in walking distance to my office.
It's like being a diamond cutter in the diamond district.
I also want to note that opening an office somewhere does not necessarily tie to remote work or not. I work remotely often and it's a huge part of my quality of life, I also have an office in SF. I don't see either changing, and they are not tied.