That there is something deeper and unknowable and "informationally huge" seems obvious. We didn't bring quarks or quasars into existence, we "discovered" them as and when we extended our senses far enough using technologies (which are themselves a result of us becoming comfortable enough with our immediate reality, as a sort of positive feedback loop).
There is every reason to suspect that this deeper reality does not stop where our technologically extended abilities peter out. Our imperfect and tentative understanding when reaching the extremes of scales (of time, space, complexity, etc) is perfectly understandable. Why should a finite carbon brain be able to map out a coherent and finite model of something much, much bigger than itself.
On the other hand over millennia of brainstorming (literally) we have collected some interesting datapoints about this deeper reality: it is not "malicious", and somehow it agrees to be mapped by us (mathematically), even if in disconnected parts.
In fact this benevolent aspect of deeper reality has made us unusually cocky. Imagine the existential angst if the universe changed its laws at whim. We'd be back to praying. E.g., that gravity remains stable for a while so that we don't drift into space. This premature self-assuredness explains repeated scientific episodes of proclaiming "we have explained everything". This also feeds the sterile chase of "a theory of everything".
In fact the limits of our understanding are in front of our eyes, everywhere. We haven't really explained a single phenomenon in the so called "complexity science" domain. Deeper reality is all around us and the most dramatic and impactful scientific revolutions are still ahead of us.