I think it’s because you lose your buccal fat. I only notice it on people who are already fairly thin and taking Ozempic.

As someone on Ozempic, and who has been through a few periods of weightless before - I'm not convinced it is just weightless. The three other people whom I know that are either on, or have used it, have all had experience with dry head and facial skin. It's not a long bow to draw to wonder if the drying is related to skin moisture and elasticity.

I've found a good vitamin a boosting skoncare regime and general face moisturiser application goes some way to noticeably reducing the flakiness and dryness.

Seems like it. When I was skinny(not a rapid weight loss, it took years), I looked very different. I look a lot more friendly when I'm fatter. My skinny face was a bit.. harsh.