Okay, so this miracle drug isn't a miracle either. Which miracle drug is?!?! I'm not asking sarcastically or ironically- I'm sincerely begging for miracles. Anyone??
https://www.astralcodexten.com/p/why-does-ozempic-cure-all-d...
Beyond their somewhat miraculous effects on obesity, they seem to have a wide variety of positive effects even for non-overweight people. They are likely the best and broadest thing we have for stopping negative addictions. They have incredibly positive effects for immune issues. Plus strong early trial results for Parkinson's, Alzheimers, and heart and kidney disease.
I also think they are underrated and there may be some alpha in them for a few reasons:
1. People seem to hate the idea that someone can "cheat" at losing weight, almost seeming to hope they have some unknown side effect.
2. People seem to dismiss them as "only working because obesity causes all those issues", probably the biggest fallacy as we have evidence already, and I think will find much more, that the addictive, immune, kidney and heart effects are not due to weight loss/fasting.
3. People don't seem to realize how huge a deal it is if they do have a strong effect on immune issues - immune system issues underly so many health issues of different names from allergies to Alzheimers to all sorts of terrible diseases, and I now know a couple non-overweight people who have reported nearly miraculous results with them.
4. Their effects on addiction likewise just by themselves are big. Another friend/smoker since high school, smokes nearly a pack a day tried it and for the first time since HS didn't smoke a cigarette for a whole day - multiple days in a row.
BTW it seems tirzepatide is significantly better for at least some of these effects than semaglutide.
(There's other interesting aspects of mph too - like how it can change sensitivities - and actually make light mode not feel like your eyes are on fire! - but that's a comment probably for another time.)
There’s an insidious issue: uninformed people tend to quickly assume that the patient is weak-willed and ate even if instructed to come NPO.
Not sure if one can call a set of drugs that are so in demand as to be basically impossible to get at times underrated. Possibly random people online say otherwise but the market says the opposite very strongly.
Take the treatments for spinal muscular atrophy. If you’re born with the worst type, you die before age 2 from respiratory failure.
Today? Start treatment at birth and you live a normal life.
There have been miracle drugs released every decade or so since the early 1900s.
They're just normal now. They stop being a miracle once we're used to them.
People used to die of fevers. Of sepsis. And there was nothing that could be done. Let alone cancer.
- Miracle drugs for curing ailments. We have plenty of those.
- Miracle drugs for enhancing beyond normal. Many things which work also have serious side-effects. Most things which are peddled with prescription don't have any effect.
IIRC it's also hard on liver, esp. in combination with alcohol (which js unfortunate since it's otherwise good for hangover).
It is particularly neat because it's not just a pain suppressant, it's a general emotion suppressant.
> ... [it] blunts physical and social pain by reducing activation in brain areas (i.e. anterior insula and anterior cingulate) thought to be related to emotional awareness and motivation. [1]
It also reduces the empathy for pain. [2]
"You rush a miracle man, you get rotten miracles."