Not sure about that. If people are convinced they are not getting along with another person because they are "lion" and then never do a real analysis of their communication failures, then I see a lot of harm for all the people around them, usually children.
If someone, even the ones who believe in astrology, believe it works that way, that's a problem with the person, not with astrology. Astrology doesn't state that x and y alone don't go well together. It points the struggles and harmonies between two sets of highly complex birth charts. Disclaimer: I don't believe in astrology, but I know a little about its ground rules.