Given that PIO's most compelling use case is replacing legacy MCUs, I find it disappointing that they haven't provided PIO boilerplate for the peripherals that keep those archaic architectures relevant. Namely: Ethernet MII and CANbus.
Also, if RP2xxx is ever going to play ball in the wireless space, then they need an out-of-box Bluetooth HCI implementation, and it needs sample code, and integration into Zephyr.
I speak as someone living in this industry: the only reason Nordic has such a firm grip on BLE product dev is because they're the only company providing a bullshit-free Bluetooth stack out of the box. Everything else about nRF sucks. If I could strap a CYW4343 to an RP2350 with some example code as easily as I can get a BT stack up and running on an nRF52840, I'd dump Nordic overnight.