I'm truly deeply sorry about this whole situation. Thank you for sharing all your knowledge.
1. Help and educate other people who are suddenly facing the opaque clinical-trial system: https://bessstillman.substack.com/p/please-be-dying-but-not-...
2. Ultimately, reform and speed FDA approval for fatal diseases like recurrent / metastatic head and neck cancers: https://jakeseliger.com/2024/01/29/the-dead-and-dying-at-the.... A drug like petosemtamab (MCLA-158), which I was on from Sept. 27 2023 to March 29 2024, should already be approved, instead of continuing to wander around in clinical trials.
Antibody drug conjugates also seem to be discussed often:
https://www.mdanderson.org/cancerwise/antibody-drug-conjugat...
He’s mentions trying drugs that target EGFR mutations, which I believe tries to stop the blood supply to the tumor. Targeting specific protein receptors, like HER2 in breast cancer, seems to be promising.
https://my.clevelandclinic.org/health/diseases/25213-her2-po...
RAS is a target for (some) colon and pancreatic cancers:
https://www.cancer.gov/research/key-initiatives/ras#:~:text=....
https://www.fda.gov/media/133864/download#:~:text=Right%20to....
The FDA is a joke. I mean that in the kindest way possible as someone with long covid waiting for the FDA to allow me access to previous covid therapeutics that show promise in this disease.
This lack of patient agency applies to all of medicine, really.
I plan to improve patient-doctor relationship in general. Gut tells me that enabling educative access to the basic sciences component of medical school and paring it down to patient specific focus, we can enable much higher patient agency through better patient-doctor communication and a deeper understanding of ones condition.
More importantly a better decision making process and ability to query and understand the doctor.
I've been through this with my wife and it's just so important.