So much of this is a blackbox that you have to wing it for lots of things and try stuff. The more compute you have, the more YOLO runs you can do.
For example, the research team I work with has about 1/20th the compute that a Google researcher has. This gives them a massive advantage because they can afford to train lots of random ideas and see what kind of advantage they get. We have to be much, much more measured and predict our outcomes better.