I still create one-off emails, but given the comparable amount of spam I get - 99% of it to a typo'ed email address from a decade ago - even that hardly seems worth it.
Also, if these numbers randomly rotate, I'd wager you'd still get spam calls, no? As one number gets "burned" (as much as a trivially-wardialable 10-digit number can be considered to be a secret), it'll be placed back into the pool, and you'll just get spam aimed at someone else.