Concentrations of people create hygenic issues regardless. On balance, Romes latrines were probably a net benefit, though of course the Romans lacked modern understanding of disease, both in parasitic and infectious forms.
Even today, roughly 85% of the increase in human longevity, much due to decreased infant and child mortality, is attributable to general hygiene, municipal sanitation measures (both of wastes such as sewerage, solid rubbish, and of improved air quality; and of vastly improved water and food quality. Other public health measures, including quarantine, epidemiological surveillance, and vaccinations, also played a huge role. I first became aware of this through Laurie Garrett's book The Coming Plague (1994): <https://search.worldcat.org/title/30701925>
See "The Conquest of Pestilence in New York City" for a ... graphic ... expression of the trends in mortality from ~1800 through 2000 or so:
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