Youth with conduct disorder show widespread differences in brain structure | Hacker News Reader

Youth with conduct disorder show widespread differences in brain structure

nih.gov

25 pointsbookofjoe8 comments

Full study: https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0...

dancing on the line between we "use" our mind, and we "are" our mind

Youth with conduct disorder had lower total surface area across the cortex and in 26 of 34 individual regions, two of which showed significant changes in cortical thickness. Youth with conduct disorder also had lower volume in several subcortical brain regions, including the amygdala, hippocampus and thalamus

tl;dr: they do have smaller brains.

That'd be the tl;dr if you actually didn't understand what that sentence said. Volume was lower in some subcortical regions. That's some parts of about a quarter of the brain.

The implied message behind your tl;dr is also missing the mark:"Most differences remained significant after adjusting for [...] intelligence quotient."

It's a bummer to see these kinds of non-thinking reddit laughlines on HN - this is actually an extremely interesting study. For a summary, I recommend the "Added Value of this study" section. One of the most interesting findings (to me, at least) is e.g. the fact that brain alterations extend well beyond emotional regulation even to temporal & motor capacities.

There are also interesting questions to pose - e.g. why the study only found ADHD in subjects with conduct disorder. (That's not an expected result in that sample size - while ADHD & CD can co-occur, ADHD without CD is significantly more common)

I think we can do better than cheap shots.

I believe there's a clear relationship between surface area and capability, having less surface area of 1/3rd of one's brain is no doubt a disadvantage.

Dang. They should have just asked you instead of doing the study.

i feel you're being a bit disingenuous. he offered a tl;dr, for someone glancing at the comments, it's a fine tl;dr. maybe not a great summary.. but it's fine as a tl;dr.

It's not even fine as tl;dr. It misrepresents the study.

Yes, it quotes some words from the study. That's not what a tl;dr is.

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