When I first heard about it I decided from now on I'll run uBlock Origin in default JavaScript off mode. It's a checkbox in the settings.
I only re-enable on a per-site basis if I have no other choice.
I prefer this over NoScript, since it's one click and I still get all the uBlock filters even after enabling JS.
I've been using web like this for over a year now, and while it's painful, it's also enlightening.