I enjoyed demoing my friend's Vision Pro but I regularly found myself displeased with the gesture controls. Once the novelty of interacting with the demo features wore off, I found myself thinking that the device was best suited as a monitor replacement. To that end, I would absolutely need to use a mouse and keyboard.
I also wonder if Apple's decision to eschew any special pointing or peripheral device in favor of hand tracking was the best idea. If I owned one of these things and used it for casual internet browsing, I would much prefer some little handheld accessory so I could press buttons without having to gesticulate and make sure my posture was correct so that the cameras could pick up my hand movements.