It's a huge fucking problem if you're not American. If you don't want to be subject to American law. If you don't want your technology inspected or tampered with by Americans. If you don't want the transaction to be in dollars (extra-territoriality of US law on all dollar transactions). If you don't want to deal with the problem of American citizens and companies subject to FISA, who could face severe repercussions in the US if they don't spy or facilitate spying on their non-American clients.