I waited too long to make an appointment once (because, you know, ADHD), and then ran into a problem that my doctor's office had reorganized duties to give the renewing prescriptions role to a newly hired nurse aid without considering that he can't refill controlled substances. I kinda wondered how that could work, but either because was new to the job or overconfident he assured me I was wrong about the legality of that and he definitely would get the prescription scrip for me.
By the time he / the doctor's office realized actually no, he can't refill my ADHD medication, my doctor was out and a four day weekend would soon begin. At this point I was already a few days off the meds and going through withdrawals, which got worse over the weekend. By the time Tuesday rolled around I'd essentially been forced to "quit" cold turkey, and so I was like, what is the point of re-starting this now I've gone through the hardest part of getting off it?