I always bounce off of Factorio because I want to be able to play with the default settings but I always end up getting killed by bugs/aliens not long after starting the game.
- Set spawn area to largest. Earliest biter nests get generated farther away, making it more difficult for your pollution cloud to reach them
This way you can play largely in peace without having achievements disabled.
It's the Factorio equivalent of the mine cart blender room trap in Dwarf Fortress, certified to kill even clown invasions.
Or just play in peaceful mode, there is still so much good gameplay left even without the challenge of biters.