From a cosmetic point of view, almost everybody exclusively focuses on the skin to counter aging, when they should be at least as concerned with bone density.

Lots of people have perfect skin, but they still look old. Why? Bone morphology. The zygomatic bone erodes, and the orbital gaps widen. The mandible degrades and pivots down and backwards (jaw rotation). Issues like resorption are currently very challenging. Skin is comparatively much easier. Also (and besides well-known interventions like collagen, retinoids, HA, and dermarolling), Epidermal and Keratinocyte Growth Factors are already very cheap, and showing much promise.