I’m guessing there aren’t many studies on this, but as a young, fast runner I’d zigzag every time if they’re shooting _at_ me. At least run in a straight line that isn’t collinear with the shooter’s position. Obviously, if you can find cover, put it between you and them and cover distance.
It’s so, so hard for any amateur to hit a target that is moving radially in a polar coordinate system centered on them, at all. I’d bet your average shooter who makes the news can’t put 7/10 shots in a stationary silhouette at 10yd. It’s harder than you’d think.