Parkinson's disease-associated SNP4 is correlated (r2=0.95) with variants that are associated with HLA-DQA2 expression.
https://www.ncbi.nlm.nih.gov/gene/3118#:~:text=HLA%2DDQA2%20....
https://www.ncbi.nlm.nih.gov/gene/3118#:~:text=HLA%2DDQA2%20....
Keeps you alive at 30, kills you at 70. You got to reproduce so it counts as a win for evolution!