Nah, if you want heavy backend, go with Go/Ktor/C#, not node. If you want light backend, use sth like Hono or H3. If you want to primarily produce html, use Remix or Next.

Adonis/Redwood/Nest is something you will regret in few years because it will lock you down to "their" ways of doing things instead of something with replaceable components.

Admitted, Adonis looks most sensible out of these 3. Redwood is poisoned with needless GraphQL and Nest is written like 2008 java. In Adonis you can at least pick the db layer.

But even Adonis locks you to their validator instead of Zod or his cousins, they use their own Request/Response classes instead of the platform ones, has yucky inheritance and annotations magic etc.