I have to work with Adobe Experience Manager and it's a weird, painful, slow/inefficient kludge, not to even get into the licensing terms and what devs are "allowed" to do on their own servers.
Acrobat Reader stands out in my memory only as that extremely slow, bloated thing you launched by accident, then closed 5 minutes later once it loaded to use Sumatara instead.
They killed Flash by neglect after buying it from Macromedia - we might still have it around if they invested in it properly and made it up to par for the iPod. Thankfully we finally have good emulators that work in the browser to see the vast amount of old Flash content.
Creative Suite is fine and mostly functional from what I hear, but they didn't make that codebase either, and I've never felt limited by free or cheaper alternatives like GIMP or Sony Vegas. (I find it baffling how people rag on GIMP - I use it in a professional and personal capacity and I love it, and I'm familiar enough with Photoshop to compare it.)