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As someone who has been a pain patient for a decade and a half, and as someone who has been supplementing with magnesium off and on for even longer... If you're a pain patient you should definitely investigate this, and probably just supplement and see how it goes. I certainly feel better about my relationship with opioids when I'm consistent about my magnesium.

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Magnesium will increase ATP. And ATP is the energy that is needed to sensitize G protein coupled receptors. One of those G protein coupled receptors is the opioid receptor.

So what magnesium is doing is making your opioid receptors more sensitive to your natural opioids.

I think severe withdrawals are associated with Magnesium deficiency. This research has been going on for decades as there isn't a dose response curve for how severe a narcotic withdrawal will be based on dosing alone.

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