We can deal with all martian problems.
1. Perchlorates in the soil? You can deal with them, say, chemically if you need some patch on Mars which is more Earth-like. After al you don't need to have the whole Mars immediately fertile.
2. Low pressure? Yes, but it's still better than vacuum, so spacesuits could be simpler, and also the cold atmosphere won't freeze you as much.
3. Far from Earth so Sun is too dim for solar batteries? Then take more of those batteries, they are becoming good, cheap and even light.
4. Far away from Earth? Yes, true - but we can survive for the year to get from here to there, and we routinely had ISS missions for half a year, comparing to ~9 months flight with today's technologies from Earth to Mars.
5. Low gravity on Mars and weightlessness in flight? Some are optimistic about artificial gravity during flights or even on the surface, and if we don't yet consider permanent settlements, it's imaginable to live a couple of years in that artificial gravity, and come back in a relatively good shape.
0. Radiation? How about better shielding for spacecrafts for the flights - both using e.g. water onboard and plasma clouds around, so different kinds of radiation would be at least reduced. Just like with artificial gravity, there are much more questions than answers in these areas, but at least we have physically plausible ideas. On the surface we can use underground houses - even with centrifuges.