Well, mostly from your incoming spam. The header you're looking for is `X-MS-Exchange-CrossTenant-Id`. If it ends in `aaaa`, don't touch it, as that's the freemail-outlook.com, but otherwise, feel free to (test-)reject it.
To get started: 41a71966-4fa6-4839-a87d-034d66bdda33 d931cb4a-3984-4328-9fb6-96d7d7fd51b0 e85f2c00-2730-4ca5-b8d8-609b15bd4746
(all seen-in-the-wild compromised instances in the past 14 days)