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Comment by akoboldfrying | Hacker News Reader

That's true if we assume unlimited resources and equal awareness/perceived social value of the two applications. But I think the former doesn't hold, and the latter is greatly influenced by sites like HN, where I'm disappointed to consistently (if not exclusively) see breathless proposals for ways to design shinier hubcaps whenever some promising new technology appears.

Yes, they can and likely will both happen to some extent, but I think they aren't independent, so I feel justified in trying to nudge the public conversation back towards the issues that I think matter more.

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In all likelihood if we were to get to the point of it being safe and cheap enough for genetic engineering cosmetic "upgrades" then that would through economies of scale drive enough money that medical research funding would be a solved problem. Also anyone wanting the chrome pipes and spoilers package is going to want their engine tuned. Whats the point of having functional wings if you heart blows out trying to use them.

Cosmetic surgery for vanity has helped improve the techniques and procedures and even the number of skilled practitioners that can then help those with disfigurements and deformities.

Hell, cancer treatment for pets has advanced human oncology [1]. Scientific discovery is rarely zero sum.

[1] https://www.upstate.edu/whatsup/2019/0220-treatment-for-cani...

And cigarettes have benefited the lung cancer research centers. Just because it works doesn’t make it the best course.

Economies of scale. Shiny hubcap manufacturers will very generously subsidise the R&D for other, more worthy users of a technology. They aren't competitive or independent, they're synergistic. The billions of dollars we "wasted" on making video games look more realistic gave us a revolution in high-performance computing that nobody could have created intentionally.

Each gene therapy is a unique "medicine". There is little economy of scale, at least for the hardest part.

That's due to a lack of theory and useful abstractions in the tools used to modify genes. We're so early on in the development of that field that if this were computers, we'd still be assembling devices by arranging logic gates by hand. Custom cosmetic gene therapy is a great way to incentivize the better tools.

No, not really.

Genes are far more complex than inserting a sequence into a delivery mechanism.

"they aren't independent"

That interdependence may be beneficial, though.

Experience and revenues from cosmetic treatments will help health-restoring treatments.

> breathless proposals for ways to design shinier hubcaps whenever some promising new technology appears

I wouldn't underestimate the emotional toil of dealing with illness and death [1].

Tackling these problems head on requires (a) exposing researchers to that toil and (b) removing from the pool anyone who doesn't want to do that. Given how much of Silicon Valley culture is built on borderline-ludicrous optimism (once it's over the border it no longer qualifies as building), it makes sense that the indirect approach finds resonance here in a way the direct one does not.

Where your argument finds ample purchase is in the asymmetry of idiot luxury spending in our society to basic and applied research of any kinds, wings or Wilm's tumour.

[1] https://www.statnews.com/2016/09/19/mental-health-doctor-res...

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