The problem is that you can issue keys without having to deploy them to a fleet of servers (you sign the user's pubkey using your SSH CA key), but you have no way of revoking them without pushing an updated revocation list to the whole fleet. We did have a few long-term keys that were issued, generally for build machines and dev environments, and had a procedure in place to push CRLs if necessary, but luckily we didn't ever end up in a situation where we had to use it.