In general, human-based space exploration makes 0 sense. We have robots that can do everything a human in a life-support suit can, and don't need to carry 100 times their mass just to not day on the way there and back. Doing a few experiments with humans in space, like we do on the ISS, is indeed worth it for exploring the unknown unknowns of biology. Maybe some day, far in the future after we have explored Mars with many hundreds of robots, it will even make sense to send a human there. But until then, it's just a waste of everything.