World-first tooth-regrowing drug will be given to humans in September
newatlas.com
newatlas.com
While he isn't the best on dental hygiene I know he tries....but his medication and genetics kinda skew any efforts he makes. He jokes that he'd be lucky to have teeth by 50 still left, and in his case I feel bad for him because he does all he really can yet still has cavities and needs fillings regularly.
I still have my teeth, but not for long (probably not to even my 40s). While teeth cleaning and tartar removal every few weeks helps slowing this process, its not going to stop it.
I pray that this breakthrough happens (even though it will probably take 5 to 10 years until we have something viable that we can pay for).
The mutation occurs naturally; if you have heard of entire families who do not get cavities or children 'growing out' of getting cavities, my understanding is that it is usually correlated with the natural spread of this variant of s.mutans.
> Lumina is a genetically engineered version of the Streptococcus mutans bacterium that lives in the mouth, and it is supposed to prevent you from developing dental caries because it does not produce acid - It has been poorly studied for safety and effectiveness - Streptococcus mutans is actually neither necessary nor sufficient for the development of dental caries; the disease actually comes about because of a shift in the equilibrium of bacteria in the mouth which encourages the demineralization of our teeth
Is there a good way to order genetic sequencing of s.mutans from my own mouth? Have we gotten to the point where a lab test like this is inexpensive enough to be done for the sake of curiosity?
Googling this seems as hard as finding good dietary info that's not diet propaganda. This dentist says sorbitol may enable tooth decaying bacteria and only xylitol is ok https://michaelsinkindds.com/sugar-substitutes-can-cause-too... but other sources say sorbitol is fine. The one thing all seem to agree on is that sorbitol is better than sugar but why is it so hard to find a toothpaste that has no sweetener in it... and that doesn't taste of mint, which is the only alternative.
I'm told I have good genes / strong teeth and I brush after every meal but somehow every year my cavities add up to my entire dental insurance budget plus a crown I never get around to fund, regardless which dentist I go to.
So yes, bring on the tooth regrowing drug! I'll give that a try.
I am a 49-year-old and (apart from the four teeth removed in my teens so that orthodontics could straighten and resolve overcrowding) at the moment I have all my teeth, wisdom teeth included.
(It looks like one wisdom tooth might not be long for this mouth, but I digress)
But once you get to this age, the density of your teeth begins to matter.
What would be really great is a treatment that would regrow gums in a meaningful, controlled way that supported reattachment; some of my gums are receding for reasons that are developmental, and some is less than ideal self-care, but much of it is just plain being a man over 40.
There are some medications that cause gum overgrowth as a side effect, but not usefully.
That is giving Channel Zero: Candle Cove vibes.
(Nightmare material)
The USAG-1 protein has a high amino acid homology of 97% between different animal species, including humans, mice, and beagles.
Really hope this trial works out. Of all the things I thought we'd be trialling regrowth of first, I would never have guessed teeth. But actually I never thought anything like this would happen in my lifetime.