If I’m not mistaken, most employers have the option to immediately terminate you as well if it was ever found that you lied in an interview to get the job.
Most employers in the US have the option to immediately terminate you for no reason at all.
Ethically: Lie about anything you want, corporations are utterly amoral entities undeserving of moral treatment.
Practically: Lie about anything you're pretty sure you can learn on the job, most companies are very slow and reluctant to fire people for performance.
The number of lies you tell in an interview is the number you will have to repay once you get the job, possibly even more.