Folklore is that Knuth hasn't used email since the 90s. You need to send dead trees to his secretary and hope she forwards it to him.
I have received one actual email from him, when I pointed out an error in the balances at the Bank of San Serriffe (https://www-cs-faculty.stanford.edu/~knuth/boss.html).
The email looks like it was typed by him - the style is right and it is signed "Don" - but the From: address has someone else's name.